Q

ellikerd asked:

What's the hardest part about rollerblading? Telling your parents you're gay.

A

olsonstuff:

Hardest part telling that joke, getting punch in the face💥

fukkkres:

bitch ur under arrest what you say and do may be used in a court of shredding *hits da blunt while doing nollie backspin* dont run from me *manuals in front of you*

backspin

fukkkres:

bitch ur under arrest what you say and do may be used in a court of shredding *hits da blunt while doing nollie backspin* dont run from me *manuals in front of you*

backspin

(via pauliegallo)

currentsinbiology:

Osteoporosis Drug Stops Growth of Breast Cancer Cells, Even in Resistant Tumors, Study Suggests

June 15, 2013 — A drug approved in Europe to treat osteoporosis has now been shown to stop the growth of breast cancer cells, even in cancers that have become resistant to current targeted therapies, according to a Duke Cancer Institute study.


The findings, presented June 15, 2013, at the annual Endocrine Society meeting in San Francisco, indicate that the drug bazedoxifene packs a powerful one-two punch that not only prevents estrogen from fueling breast cancer cell growth, but also flags the estrogen receptor for destruction.

"We found bazedoxifene binds to the estrogen receptor and interferes with its activity, but the surprising thing we then found was that it also degrades the receptor; it gets rid of it,” said senior author Donald McDonnell, PhD, chair of Duke’s Department of Pharmacology and Cancer Biology.

More at Science Daily

Image: Osteoporosis in vertebra showing 3 microfractures
Dr. Michael Klein University of Alabama, AL
Polarized light, 15x Objective

(via bloomwitch)

Drippy

Is this what December looks like?

Finally figured out the time machine

Sunny southern Florida

Bayliss and his new toy
#sorryforpuppying